5zim
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of bacteriorhodopsin at 1.25 A resolution== | |
| + | <StructureSection load='5zim' size='340' side='right' caption='[[5zim]], [[Resolution|resolution]] 1.25Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5zim]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halobacterium_salinarum Halobacterium salinarum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZIM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZIM FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=L2P:2,3-DI-PHYTANYL-GLYCEROL'>L2P</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zim FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zim OCA], [http://pdbe.org/5zim PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zim RCSB], [http://www.ebi.ac.uk/pdbsum/5zim PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zim ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BACR_HALSA BACR_HALSA]] Light-driven proton pump. | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Bacteriorhodopsin (bR) of Halobacterium salinarum is a membrane protein that acts as a light-driven proton pump. bR and its homologues have recently been utilized in optogenetics and other applications. Although the structures of those have been reported so far, the resolutions are not sufficient for elucidation of the intrinsic structural features critical to the color tuning and ion pumping properties. Here we report the accurate crystallographic analysis of bR in the ground state. The influence of X-rays was suppressed by collecting the data under a low irradiation dose at 15 K. Consequently, individual atoms could be separately observed in the electron density map at better than 1.3 A resolution. Residues from Thr5 to Ala233 were continuously constructed in the model. The twist of the retinal polyene was determined to be different from those in the previous models. Two conformations were observed for the proton release region. We discuss the meaning of these fine structural features. | ||
| - | + | X-ray structure analysis of bacteriorhodopsin at 1.3 A resolution.,Hasegawa N, Jonotsuka H, Miki K, Takeda K Sci Rep. 2018 Sep 3;8(1):13123. doi: 10.1038/s41598-018-31370-0. PMID:30177765<ref>PMID:30177765</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | [[Category: | + | <div class="pdbe-citations 5zim" style="background-color:#fffaf0;"></div> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Halobacterium salinarum]] | ||
[[Category: Hasegawa, N]] | [[Category: Hasegawa, N]] | ||
[[Category: Jonotsuka, H]] | [[Category: Jonotsuka, H]] | ||
[[Category: Miki, K]] | [[Category: Miki, K]] | ||
| + | [[Category: Takeda, K]] | ||
| + | [[Category: Membrane protein]] | ||
| + | [[Category: Proton pump]] | ||
| + | [[Category: Proton transport]] | ||
Revision as of 08:00, 10 October 2018
Crystal structure of bacteriorhodopsin at 1.25 A resolution
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