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6b71
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(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with3-(4-chlorophenyl)-5H,6H-imidazo[2,1-b][1,3]thiazole== | |
| - | + | <StructureSection load='6b71' size='340' side='right' caption='[[6b71]], [[Resolution|resolution]] 1.52Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6b71]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B71 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B71 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A5H:3-(4-chlorophenyl)-5,6-dihydroimidazo[2,1-b][1,3]thiazole'>A5H</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr> | |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr> |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5cxq|5cxq]]</td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6b71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b71 OCA], [http://pdbe.org/6b71 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b71 RCSB], [http://www.ebi.ac.uk/pdbsum/6b71 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b71 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/A0A0U3AGT1_SCHMA A0A0U3AGT1_SCHMA]] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.[PIRNR:PIRNR000477] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Purine-nucleoside phosphorylase]] | ||
| + | [[Category: Barbosa, J A.R G]] | ||
| + | [[Category: Bird, L]] | ||
[[Category: Collins, P]] | [[Category: Collins, P]] | ||
| - | [[Category: | + | [[Category: Delft, F V]] |
| - | + | ||
| - | + | ||
[[Category: Faheem, M]] | [[Category: Faheem, M]] | ||
| - | [[Category: | + | [[Category: Neto, J B]] |
| - | [[Category: | + | [[Category: Pearce, N M]] |
| - | [[Category: Valadares, N | + | [[Category: Pereira, H M]] |
| + | [[Category: Valadares, N F]] | ||
| + | [[Category: Purine nucleoside phosphorylase]] | ||
| + | [[Category: Transferase]] | ||
| + | [[Category: Transferase-inhibitor complex]] | ||
Revision as of 08:04, 10 October 2018
Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with3-(4-chlorophenyl)-5H,6H-imidazo[2,1-b][1,3]thiazole
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