6hjc
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Loei River virus GP1 glycoprotein at pH 8.0== | |
| - | + | <StructureSection load='6hjc' size='340' side='right' caption='[[6hjc]], [[Resolution|resolution]] 2.51Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6hjc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HJC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HJC FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hjc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hjc OCA], [http://pdbe.org/6hjc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hjc RCSB], [http://www.ebi.ac.uk/pdbsum/6hjc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hjc ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/A0A023J4Z7_9VIRU A0A023J4Z7_9VIRU]] Glycoprotein G1: interacts with the host receptor.[HAMAP-Rule:MF_04084] Glycoprotein G2: class I viral fusion protein that directs fusion of viral and host endosomal membranes, leading to delivery of the nucleocapsid into the cytoplasm. Membrane fusion is mediated by irreversible conformational changes induced upon acidification in the endosome.[HAMAP-Rule:MF_04084] Stable signal peptide (SSP): cleaved and functions as a signal peptide. In addition, it is also retained as the third component of the GP complex. The SSP is required for efficient glycoprotein expression, post-translational maturation cleavage of GP1 and GP2, glycoprotein transport to the cell surface plasma membrane, formation of infectious virus particles, and acid pH-dependent glycoprotein-mediated cell fusion.[HAMAP-Rule:MF_04084] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bowden, T A]] | ||
| + | [[Category: Ng, W M]] | ||
| + | [[Category: Omari, K El]] | ||
[[Category: Pryce, R]] | [[Category: Pryce, R]] | ||
[[Category: Wagner, A]] | [[Category: Wagner, A]] | ||
| - | [[Category: Bowden, T.A]] | ||
| - | [[Category: Ng, W.M]] | ||
[[Category: Watanabe, Y]] | [[Category: Watanabe, Y]] | ||
| + | [[Category: Zeltina, A]] | ||
| + | [[Category: Attachment]] | ||
| + | [[Category: Glycoprotein]] | ||
| + | [[Category: Viral protein]] | ||
Revision as of 08:16, 10 October 2018
Crystal structure of Loei River virus GP1 glycoprotein at pH 8.0
| |||||||||||
Categories: Bowden, T A | Ng, W M | Omari, K El | Pryce, R | Wagner, A | Watanabe, Y | Zeltina, A | Attachment | Glycoprotein | Viral protein
