2r9s

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|PDB= 2r9s |SIZE=350|CAPTION= <scene name='initialview01'>2r9s</scene>, resolution 2.400&Aring;
|PDB= 2r9s |SIZE=350|CAPTION= <scene name='initialview01'>2r9s</scene>, resolution 2.400&Aring;
|SITE=
|SITE=
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|LIGAND= <scene name='pdbligand=255:N-(tert-butyl)-4-[5-(pyridin-2-ylamino)quinolin-3-yl]benzenesulfonamide'>255</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>, <scene name='pdbligand=TFA:TRIFLUOROACETYL+GROUP'>TFA</scene> and <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>
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|LIGAND= <scene name='pdbligand=255:N-(TERT-BUTYL)-4-[5-(PYRIDIN-2-YLAMINO)QUINOLIN-3-YL]BENZENESULFONAMIDE'>255</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=OCY:HYDROXYETHYLCYSTEINE'>OCY</scene>, <scene name='pdbligand=TFA:TRIFLUOROACETYL+GROUP'>TFA</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase Mitogen-activated protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.24 2.7.11.24]
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase Mitogen-activated protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.24 2.7.11.24] </span>
|GENE= MAPK10, JNK3, JNK3A, PRKM10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= MAPK10, JNK3, JNK3A, PRKM10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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|DOMAIN=
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r9s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r9s OCA], [http://www.ebi.ac.uk/pdbsum/2r9s PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2r9s RCSB]</span>
}}
}}
'''c-Jun N-terminal Kinase 3 with 3,5-Disubstituted Quinoline inhibitor'''
'''c-Jun N-terminal Kinase 3 with 3,5-Disubstituted Quinoline inhibitor'''
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==Disease==
 
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Known diseases associated with this structure: Epileptic encephalopathy, Lennox-Gastaut type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602897 602897]]
 
==About this Structure==
==About this Structure==
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[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Habel, J E.]]
[[Category: Habel, J E.]]
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[[Category: 255]]
 
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[[Category: EDO]]
 
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[[Category: TFA]]
 
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[[Category: UNX]]
 
[[Category: jnk3]]
[[Category: jnk3]]
[[Category: signaling protein]]
[[Category: signaling protein]]
[[Category: transferase]]
[[Category: transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:33:53 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:57:58 2008''

Revision as of 01:58, 31 March 2008


PDB ID 2r9s

Drag the structure with the mouse to rotate
, resolution 2.400Å
Ligands: , , , ,
Gene: MAPK10, JNK3, JNK3A, PRKM10 (Homo sapiens)
Activity: Mitogen-activated protein kinase, with EC number 2.7.11.24
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



c-Jun N-terminal Kinase 3 with 3,5-Disubstituted Quinoline inhibitor


About this Structure

2R9S is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Mon Mar 31 04:57:58 2008

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