6c6i
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of a chimeric NDM-1 metallo-beta-lactamase harboring the IMP-1 L3 loop== | |
| - | + | <StructureSection load='6c6i' size='340' side='right' caption='[[6c6i]], [[Resolution|resolution]] 1.65Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6c6i]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C6I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6C6I FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4hl2|4hl2]]</td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6c6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c6i OCA], [http://pdbe.org/6c6i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6c6i RCSB], [http://www.ebi.ac.uk/pdbsum/6c6i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6c6i ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BLAN1_KLEPN BLAN1_KLEPN]] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Beta-lactamase]] | ||
[[Category: Bonomo, R]] | [[Category: Bonomo, R]] | ||
| + | [[Category: Giannini, E]] | ||
| + | [[Category: Klinke, S]] | ||
| + | [[Category: Llarrull, L]] | ||
[[Category: Mojica, M]] | [[Category: Mojica, M]] | ||
| + | [[Category: Otero, L]] | ||
[[Category: Palacios, A]] | [[Category: Palacios, A]] | ||
| - | [[Category: Klinke, S]] | ||
| - | [[Category: Giannini, E]] | ||
| - | [[Category: Otero, L]] | ||
[[Category: Vila, A]] | [[Category: Vila, A]] | ||
| - | [[Category: | + | [[Category: Chimeric protein]] |
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Ndm-1]] | ||
| + | [[Category: Zn-contaning protein]] | ||
Revision as of 07:55, 17 October 2018
Crystal structure of a chimeric NDM-1 metallo-beta-lactamase harboring the IMP-1 L3 loop
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Categories: Beta-lactamase | Bonomo, R | Giannini, E | Klinke, S | Llarrull, L | Mojica, M | Otero, L | Palacios, A | Vila, A | Chimeric protein | Hydrolase | Ndm-1 | Zn-contaning protein
