6e3j
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Human Bfl-1 in complex with the Bfl-1-specific designed peptide srt.F10== | |
| - | + | <StructureSection load='6e3j' size='340' side='right' caption='[[6e3j]], [[Resolution|resolution]] 1.48Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6e3j]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E3J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6E3J FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6e3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e3j OCA], [http://pdbe.org/6e3j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6e3j RCSB], [http://www.ebi.ac.uk/pdbsum/6e3j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6e3j ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/B2LA1_HUMAN B2LA1_HUMAN]] Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Jenson, J M]] | ||
| + | [[Category: Keating, A E]] | ||
| + | [[Category: Anti-apoptotic bcl-2]] | ||
| + | [[Category: Apoptosis]] | ||
| + | [[Category: Design]] | ||
| + | [[Category: Inhibitor]] | ||
Revision as of 08:00, 17 October 2018
Human Bfl-1 in complex with the Bfl-1-specific designed peptide srt.F10
| |||||||||||
