6g31
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human geranylgeranyl diphosphate synthase mutant D188Y bound to zoledronate== | |
| - | + | <StructureSection load='6g31' size='340' side='right' caption='[[6g31]], [[Resolution|resolution]] 3.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6g31]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6G31 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6G31 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZOL:ZOLEDRONIC+ACID'>ZOL</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6g31 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6g31 OCA], [http://pdbe.org/6g31 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6g31 RCSB], [http://www.ebi.ac.uk/pdbsum/6g31 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6g31 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GGPPS_HUMAN GGPPS_HUMAN]] Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Ben-Bassat, A]] | ||
| + | [[Category: Giladi, M]] | ||
| + | [[Category: Haitin, Y]] | ||
| + | [[Category: Kapelushnik, N]] | ||
| + | [[Category: Khananshvili, D]] | ||
| + | [[Category: Lisnyansky, M]] | ||
| + | [[Category: Loewenstein, A]] | ||
| + | [[Category: Marom, M]] | ||
| + | [[Category: Bisphosphonate]] | ||
| + | [[Category: Geranylgeranyl diphosphate synthase]] | ||
| + | [[Category: Ggpp]] | ||
| + | [[Category: Mevalonate pathway]] | ||
| + | [[Category: Prenyltransferase]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 08:05, 17 October 2018
Crystal structure of human geranylgeranyl diphosphate synthase mutant D188Y bound to zoledronate
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