6hrl
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the Kelch domain of human KLHL17== | |
| - | + | <StructureSection load='6hrl' size='340' side='right' caption='[[6hrl]], [[Resolution|resolution]] 2.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6hrl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HRL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HRL FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hrl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hrl OCA], [http://pdbe.org/6hrl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hrl RCSB], [http://www.ebi.ac.uk/pdbsum/6hrl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hrl ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/KLH17_HUMAN KLH17_HUMAN]] Substrate-recognition component of some cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex. The BCR(KLHL17) mediates the ubiquitination and subsequenct degradation of GLUR6. May play a role in the actin-based neuronal function (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Arrowsmith, F]] | ||
| + | [[Category: Bountra, C]] | ||
| + | [[Category: Bullock, A N]] | ||
[[Category: Burgess-Brown, N]] | [[Category: Burgess-Brown, N]] | ||
| + | [[Category: Chen, Z]] | ||
| + | [[Category: Delft, F von]] | ||
| + | [[Category: Edwards, C H]] | ||
| + | [[Category: Newman, J A]] | ||
[[Category: Shrestha, L]] | [[Category: Shrestha, L]] | ||
| - | [[Category: | + | [[Category: Sorrell, F J]] |
| - | + | ||
[[Category: Williams, E]] | [[Category: Williams, E]] | ||
| - | [[Category: | + | [[Category: Actinfilin]] |
| - | [[Category: | + | [[Category: Cullin 3 e3 ligase substrate adaptor]] |
| - | [[Category: | + | [[Category: Homo sapien]] |
| - | [[Category: | + | [[Category: Kelch domain]] |
| - | [[Category: | + | [[Category: Ligase]] |
| - | [[Category: | + | [[Category: Ubiquitination]] |
Revision as of 08:12, 17 October 2018
Crystal structure of the Kelch domain of human KLHL17
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