6mlu
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of lipid droplet formation protein Seipin/BSCL2== | |
| - | + | <StructureSection load='6mlu' size='340' side='right' caption='[[6mlu]], [[Resolution|resolution]] 4.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6mlu]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MLU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MLU FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6mlu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mlu OCA], [http://pdbe.org/6mlu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6mlu RCSB], [http://www.ebi.ac.uk/pdbsum/6mlu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6mlu ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BSCL2_DROME BSCL2_DROME]] Is a regulator of lipid catabolism essential for adipocyte differentiation. May also be involved in the central regulation of energy homeostasis (By similarity). Necessary for correct lipid storage and lipid droplets maintenance; plays a tissue-autonomous role in controlling lipid storage in adipocytes and in preventing ectopic lipid droplet formation in non-adipose tissues. May participate in phosphatidic acid metabolism and subsequently down-regulate lipogenesis.[UniProtKB:Q9Z2E9]<ref>PMID:21533227</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Arlt, H]] | ||
| + | [[Category: Farese, V R]] | ||
| + | [[Category: Liao, M]] | ||
[[Category: Sui, X]] | [[Category: Sui, X]] | ||
| - | [[Category: Walther, C | + | [[Category: Walther, C T]] |
| - | [[Category: | + | [[Category: Lipid droplet formation]] |
| - | [[Category: | + | [[Category: Lipid storage]] |
| - | [[Category: | + | [[Category: Lipodystrophy]] |
| + | [[Category: Membrane protein]] | ||
Revision as of 08:14, 17 October 2018
Cryo-EM structure of lipid droplet formation protein Seipin/BSCL2
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