Proteopedia:Featured ART/0

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<tr><td>[[Image:Oct2017sq.png]]</td></tr>
<tr><td>[[Image:Oct2017sq.png]]</td></tr>
<tr><td><div class="scrolling">'''Opening a Gate to Human Health'''<br>
<tr><td><div class="scrolling">'''Opening a Gate to Human Health'''<br>
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''by Alice Clark''<br>
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''by Alice Clark'' (PDBe)<br>
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In the 1970s, an exciting discovery of a family of medicines was made by the Japanese scientist Satoshi Ōmura. It is one of these molecules which features in this artwork, created by Alice Clark from PDBe. It shows ivermectin bound in the ligand binding pocket of the Farnesoid X receptor, a protein which helps regulate cholesterol in humans. This structure showed that ivermectin induced transcriptional activity of FXR and could be used to regulate metabolism. The scientists suggest FXR as a potential mammalian drug target of ivermectin.
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In the 1970s, an exciting discovery of a family of medicines was made by the Japanese scientist Satoshi Ōmura. One of these molecules, '''ivermectin''', is shown in this artwork bound in the ligand binding pocket of the Farnesoid X receptor, a protein which helps regulate cholesterol in humans. This structure showed that ivermectin induced transcriptional activity of FXR and could be used to regulate metabolism.
>>> [[Art:Opening_a_Gate_to_Human_Health|Visit this page]] >>>
>>> [[Art:Opening_a_Gate_to_Human_Health|Visit this page]] >>>

Revision as of 19:01, 18 October 2018

Image:Oct2017sq.png
Opening a Gate to Human Health

by Alice Clark (PDBe)
In the 1970s, an exciting discovery of a family of medicines was made by the Japanese scientist Satoshi Ōmura. One of these molecules, ivermectin, is shown in this artwork bound in the ligand binding pocket of the Farnesoid X receptor, a protein which helps regulate cholesterol in humans. This structure showed that ivermectin induced transcriptional activity of FXR and could be used to regulate metabolism.

>>> Visit this page >>>

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Jaime Prilusky, Angel Herraez

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