Ribosomal protein L2

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<StructureSection load='1rl2' size='350' side='right' caption='Se-Met structure of ribosomal protein L2 [[1rl2]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='1rl2' size='350' side='right' caption='Se-Met structure of ribosomal protein L2 [[1rl2]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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[[Ribosomal protein L2]] (RPL2) is one of the 34 proteins which belong to the <scene name='Ribosomal_protein_L2/Cv/2'>large 50S subunit</scene> of the prokaryotic ribosome or to the ca. 49 proteins in the large 60S subunit of the eukaryotic ribosome. It is required for the association of the 30S and 50S subunits and is involved in the binding of tRNA at the A- and P-sites<ref>PMID:20097853</ref>. In the archaea like in ''Haloarcula marismortui'', the L2 is called L2P (RPL2P). The structure of the RNA-binding domain of L2 from Bacillus stearothermophilus is shown on the right<ref>PMID:10075918</ref>.
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[[Ribosomal protein L2]] (RPL2) is one of the 34 proteins which belong to the <scene name='Ribosomal_protein_L2/Cv/2'>large 50S subunit</scene> of the prokaryotic ribosome or to the ca. 49 proteins in the large 60S subunit of the eukaryotic ribosome. It is required for the association of the 30S and 50S subunits and is involved in the binding of tRNA at the A- and P-sites<ref>PMID:20097853</ref>. In the archaea like in ''Haloarcula marismortui'', the L2 is called L2P (RPL2P). The structure of the RNA-binding domain of L2 from ''Bacillus stearothermophilus'' is shown on the right<ref>PMID:10075918</ref>.

Revision as of 07:36, 22 October 2018

Se-Met structure of ribosomal protein L2 1rl2, resolution 2.30Å

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3D Structures of Ribosomal protein L2

Updated on 22-October-2018

References

  1. ↑ Rippa V, Cirulli C, Di Palo B, Doti N, Amoresano A, Duilio A. The ribosomal protein L2 interacts with the RNA polymerase alpha subunit and acts as a transcription modulator in Escherichia coli. J Bacteriol. 2010 Apr;192(7):1882-9. doi: 10.1128/JB.01503-09. Epub 2010 Jan 22. PMID:20097853 doi:http://dx.doi.org/10.1128/JB.01503-09
  2. ↑ Nakagawa A, Nakashima T, Taniguchi M, Hosaka H, Kimura M, Tanaka I. The three-dimensional structure of the RNA-binding domain of ribosomal protein L2; a protein at the peptidyl transferase center of the ribosome. EMBO J. 1999 Mar 15;18(6):1459-67. PMID:10075918 doi:10.1093/emboj/18.6.1459

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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