5ykj
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Structural basis of the thiol resolving mechanism in yeast mitochondrial 1-Cys peroxiredoxin via glutathione/thioredoxin systems== | |
| - | + | <StructureSection load='5ykj' size='340' side='right' caption='[[5ykj]], [[Resolution|resolution]] 1.53Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5ykj]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YKJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YKJ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr> |
| - | [[Category: Li, C | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peroxiredoxin Peroxiredoxin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.15 1.11.1.15] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ykj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ykj OCA], [http://pdbe.org/5ykj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ykj RCSB], [http://www.ebi.ac.uk/pdbsum/5ykj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ykj ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PRX1_YEAST PRX1_YEAST]] Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Involved in mitochondrial protection of cadmium-induced oxidative stress.<ref>PMID:10821871</ref> <ref>PMID:19332553</ref> <ref>PMID:20059400</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Peroxiredoxin]] | ||
| + | [[Category: Bao, R]] | ||
| + | [[Category: He, L H]] | ||
| + | [[Category: Li, C C]] | ||
| + | [[Category: Li, T]] | ||
[[Category: Liu, L]] | [[Category: Liu, L]] | ||
| + | [[Category: Peng, C T]] | ||
| + | [[Category: Song, Y J]] | ||
[[Category: Yang, J]] | [[Category: Yang, J]] | ||
| + | [[Category: Yang, M J]] | ||
[[Category: Zhao, C]] | [[Category: Zhao, C]] | ||
| - | [[Category: | + | [[Category: Zhao, N L]] |
| - | [[Category: | + | [[Category: Zhu, Y B]] |
| - | + | [[Category: 1-cys peroxiredoxin]] | |
| - | [[Category: | + | [[Category: Glutathione]] |
| - | [[Category: | + | [[Category: Saccharomyces cerevisiae]] |
| - | [[Category: | + | [[Category: Thioredoxin]] |
| - | [[Category: | + | [[Category: Transferase]] |
| - | [[Category: | + | |
Revision as of 05:44, 24 October 2018
Structural basis of the thiol resolving mechanism in yeast mitochondrial 1-Cys peroxiredoxin via glutathione/thioredoxin systems
| |||||||||||
Categories: Peroxiredoxin | Bao, R | He, L H | Li, C C | Li, T | Liu, L | Peng, C T | Song, Y J | Yang, J | Yang, M J | Zhao, C | Zhao, N L | Zhu, Y B | 1-cys peroxiredoxin | Glutathione | Saccharomyces cerevisiae | Thioredoxin | Transferase
