5zne

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'''Unreleased structure'''
 
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The entry 5zne is ON HOLD until Paper Publication
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==The crystal structure of immune receptor RGA5A_S of resistance protein Pia from rice (Oryza sativa)==
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<StructureSection load='5zne' size='340' side='right' caption='[[5zne]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5zne]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZNE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZNE FirstGlance]. <br>
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Description:
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zne OCA], [http://pdbe.org/5zne PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zne RCSB], [http://www.ebi.ac.uk/pdbsum/5zne PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zne ProSAT]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/RGA5R_ORYSJ RGA5R_ORYSJ]] Disease resistance (R) protein that recognizes the AVR-Pia and AVR1-CO39 effector avirulence proteins from M.oryzae. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth. Contribution of RGA4 is required to recognize the effector avirulence proteins AVR-Pia and AVR1-CO39 from M.oryzae (PubMed:21251109, PubMed:23548743). Acts as a repressor of the RGA4-mediated cell death activation. Upon infection, recognition and binding of the AVR effectors relieve the RGA5-mediated repression and triggers the hypersensitive response (PubMed:25024433). Immune response triggered by the RGA4-RGA5 -mediated recognition of AVR1-CO39 confers resistance to X.oryzae pathovars (PubMed:27289079).<ref>PMID:21251109</ref> <ref>PMID:23548743</ref> <ref>PMID:25024433</ref> <ref>PMID:27289079</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Guo, L W]]
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[[Category: Huang, D]]
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[[Category: Liu, J F]]
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[[Category: Peng, Y L]]
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[[Category: Plant protein]]
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[[Category: Resistance protein]]
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[[Category: Rga5a_]]
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[[Category: Rice]]

Revision as of 05:48, 24 October 2018

The crystal structure of immune receptor RGA5A_S of resistance protein Pia from rice (Oryza sativa)

5zne, resolution 1.78Å

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