2tmk

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|PDB= 2tmk |SIZE=350|CAPTION= <scene name='initialview01'>2tmk</scene>, resolution 2.4&Aring;
|PDB= 2tmk |SIZE=350|CAPTION= <scene name='initialview01'>2tmk</scene>, resolution 2.4&Aring;
|SITE=
|SITE=
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|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=ATM:3&#39;-AZIDO-3&#39;-DEOXYTHYMIDINE-5&#39;-MONOPHOSPHATE'>ATM</scene>
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|LIGAND= <scene name='pdbligand=ATM:3&#39;-AZIDO-3&#39;-DEOXYTHYMIDINE-5&#39;-MONOPHOSPHATE'>ATM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9]
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9] </span>
|GENE= CDC8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])
|GENE= CDC8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])
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|DOMAIN=
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2tmk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2tmk OCA], [http://www.ebi.ac.uk/pdbsum/2tmk PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2tmk RCSB]</span>
}}
}}
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[[Category: Lavie, A.]]
[[Category: Lavie, A.]]
[[Category: Schlichting, I.]]
[[Category: Schlichting, I.]]
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[[Category: ATM]]
 
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[[Category: SO4]]
 
[[Category: azt]]
[[Category: azt]]
[[Category: enzyme]]
[[Category: enzyme]]
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[[Category: transferase (phosphotransferase)]]
[[Category: transferase (phosphotransferase)]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 23 15:50:51 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:03:59 2008''

Revision as of 02:04, 31 March 2008


PDB ID 2tmk

Drag the structure with the mouse to rotate
, resolution 2.4Å
Ligands: ,
Gene: CDC8 (Saccharomyces cerevisiae)
Activity: dTMP kinase, with EC number 2.7.4.9
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



YEAST THYMIDYLATE KINASE COMPLEXED WITH 3'-AZIDO-3'-DEOXYTHYMIDINE MONOPHOSPHATE (AZT-MP)


About this Structure

2TMK is a Single protein structure of sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

Structure of thymidylate kinase reveals the cause behind the limiting step in AZT activation., Lavie A, Vetter IR, Konrad M, Goody RS, Reinstein J, Schlichting I, Nat Struct Biol. 1997 Aug;4(8):601-4. PMID:9253404

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