This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3a6p
From Proteopedia
| Line 1: | Line 1: | ||
| + | |||
==Crystal structure of Exportin-5:RanGTP:pre-miRNA complex== | ==Crystal structure of Exportin-5:RanGTP:pre-miRNA complex== | ||
<StructureSection load='3a6p' size='340' side='right' caption='[[3a6p]], [[Resolution|resolution]] 2.92Å' scene=''> | <StructureSection load='3a6p' size='340' side='right' caption='[[3a6p]], [[Resolution|resolution]] 2.92Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3a6p]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3a6p]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Canlf Canlf] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A6P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3A6P FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">XPO5, KIAA1291, RANBP21 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), RAN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9615 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">XPO5, KIAA1291, RANBP21 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), RAN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9615 CANLF])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a6p OCA], [http://pdbe.org/3a6p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3a6p RCSB], [http://www.ebi.ac.uk/pdbsum/3a6p PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a6p OCA], [http://pdbe.org/3a6p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3a6p RCSB], [http://www.ebi.ac.uk/pdbsum/3a6p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3a6p ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| Line 14: | Line 15: | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a6/3a6p_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a6/3a6p_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
| Line 37: | Line 38: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Canlf]] |
[[Category: Human]] | [[Category: Human]] | ||
[[Category: Katahira, J]] | [[Category: Katahira, J]] | ||
Revision as of 08:05, 24 October 2018
Crystal structure of Exportin-5:RanGTP:pre-miRNA complex
| |||||||||||
Categories: Canlf | Human | Katahira, J | Lee, S J | Nakagawa, A | Okada, C | Shibata, S | Tsukihara, T | Yamashita, E | Yoneda, Y | Cell cycle | Cell division | Exportin-5 | Gtp-binding | Importin-beta family | Isopeptide bond | Mitosis | Nuclearexport | Nucleotide-binding | Nucleus | Phosphoprotein | Pre-microrna | Protein transport | Protein transport-nuclear protein-rna complex | Rangtp | Rna-binding | Rna-mediated gene silencing | Transport | Trna-binding

