Polycomb proteins
From Proteopedia
(Difference between revisions)
(New page: <StructureSection load='5hyn' size='340' side='right' caption='Caption for this structure' scene=''> == Function == Polycomb group (PcG) proteins are determinants of gene silencing and ...) |
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== Disease == | == Disease == | ||
| - | + | Misregulation of PcG protein levels often lead to either a block or unscheduled activation of developmental pathways. the consequences of this misregulation have been linked to the establishment of cancer stem cells which can produce tumors. Cancer stem cells are believed to persist within tumors and to elicit relapse and metastasis | |
== Structural highlights == | == Structural highlights == | ||
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| - | ==3D structures of | + | ==3D structures of polycomb proteins== |
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
Revision as of 10:27, 29 October 2018
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3D structures of polycomb proteins
Updated on 29-October-2018
References
- ↑ Hauri S, Comoglio F, Seimiya M, Gerstung M, Glatter T, Hansen K, Aebersold R, Paro R, Gstaiger M, Beisel C. A High-Density Map for Navigating the Human Polycomb Complexome. Cell Rep. 2016 Oct 4;17(2):583-595. doi: 10.1016/j.celrep.2016.08.096. PMID:27705803 doi:http://dx.doi.org/10.1016/j.celrep.2016.08.096
