This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5z4a
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Structure of Tailor in complex with AGU RNA== | |
| - | + | <StructureSection load='5z4a' size='340' side='right' caption='[[5z4a]], [[Resolution|resolution]] 1.64Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5z4a]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Z4A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Z4A FirstGlance]. <br> | |
| - | + | </td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA_uridylyltransferase RNA uridylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.52 2.7.7.52] </span></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5z4a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5z4a OCA], [http://pdbe.org/5z4a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5z4a RCSB], [http://www.ebi.ac.uk/pdbsum/5z4a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5z4a ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TUTT_DROME TUTT_DROME]] Uridylyltransferase which mediates terminal uridylation of miRNAs, leading to their degradation. Has high specificity for splicing-derived miRNAs (mirtrons) and other miRNA substrates containing a 3'-G terminal nucleotide. Appears to be a major suppressor of mirtron biogenesis.<ref>PMID:26145174</ref> <ref>PMID:26145176</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: RNA uridylyltransferase]] | ||
[[Category: Cheng, L]] | [[Category: Cheng, L]] | ||
| - | [[Category: Yu, H]] | ||
[[Category: Gong, Q]] | [[Category: Gong, Q]] | ||
| + | [[Category: Jiang, Y]] | ||
| + | [[Category: Li, F]] | ||
[[Category: Shi, Y]] | [[Category: Shi, Y]] | ||
| - | [[Category: Jiang, Y]] | ||
[[Category: Xie, C]] | [[Category: Xie, C]] | ||
| - | [[Category: | + | [[Category: Yu, H]] |
| + | [[Category: Terminal uridylyltransferase]] | ||
| + | [[Category: Transferase-rna complex]] | ||
Revision as of 06:45, 31 October 2018
Structure of Tailor in complex with AGU RNA
| |||||||||||
