6hsf

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'''Unreleased structure'''
 
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The entry 6hsf is ON HOLD until Paper Publication
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==Crystal structure of Schistosoma mansoni HDAC8 mutant H292M complexed with PCI-34051==
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<StructureSection load='6hsf' size='340' side='right' caption='[[6hsf]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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Authors: Shaik, T.B., Marek, M., Romier, C.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6hsf]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HSF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HSF FirstGlance]. <br>
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Description: Crystal structure of Schistosoma mansoni HDAC8 mutant H292M complexed with PCI-34051
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMF:DIMETHYLFORMAMIDE'>DMF</scene>, <scene name='pdbligand=GKW:1-[(4-methoxyphenyl)methyl]-~{N}-oxidanyl-indole-6-carboxamide'>GKW</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_deacetylase Histone deacetylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.98 3.5.1.98] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hsf OCA], [http://pdbe.org/6hsf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hsf RCSB], [http://www.ebi.ac.uk/pdbsum/6hsf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hsf ProSAT]</span></td></tr>
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</table>
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__TOC__
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</StructureSection>
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[[Category: Histone deacetylase]]
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[[Category: Marek, M]]
[[Category: Romier, C]]
[[Category: Romier, C]]
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[[Category: Marek, M]]
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[[Category: Shaik, T B]]
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[[Category: Shaik, T.B]]
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[[Category: Epigenetic]]
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[[Category: Hdac8]]
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[[Category: Hydrolase]]
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[[Category: Pathogen]]
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[[Category: Selective inhibitor]]

Revision as of 06:58, 31 October 2018

Crystal structure of Schistosoma mansoni HDAC8 mutant H292M complexed with PCI-34051

6hsf, resolution 1.90Å

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