NADH-cytochrome b5 reductase

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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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[[1umk]] - hB5R + FAD - human<br />
+
[[1umk]] - hb5R + FAD - human<br />
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[[3w5h]], [[5gv7]], [[5gv8]], [[1ndh]], [[3w2e]], [[3w2f]], [[3w2g]], [[3w2h]], [[3w2i]] - B5R 3 + FAD + NAD - pig<br />
+
[[3w5h]], [[5gv7]], [[5gv8]], [[1ndh]], [[3w2e]], [[3w2f]], [[3w2g]], [[3w2h]], [[3w2i]] - b5R 3 + FAD + NAD - pig<br />
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[[1i7p]] - rB5R soluble domain + FAD - rat<br />
+
[[1i7p]] - rb5R soluble domain + FAD - rat<br />
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[[1qx4]] - rB5R soluble domain (mutant) + FAD <br />
+
[[1qx4]] - rb5R soluble domain (mutant) + FAD <br />
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[[1ib0]] - rB5R soluble domain + FAD + NAD<br />
+
[[1ib0]] - rb5R soluble domain + FAD + NAD<br />
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[[2eix]] - B5R + FAD - ''Physarum polycephalum''<br />
+
[[2eix]] - b5R + FAD - ''Physarum polycephalum''<br />
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 10:36, 31 October 2018

Pig b5R 3 complex with FAD and glycerol (PDB code 5gv7)

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3D structures of NADH-cytochrome b5 reductase

Updated on 31-October-2018

1umk - hb5R + FAD - human
3w5h, 5gv7, 5gv8, 1ndh, 3w2e, 3w2f, 3w2g, 3w2h, 3w2i - b5R 3 + FAD + NAD - pig
1i7p - rb5R soluble domain + FAD - rat
1qx4 - rb5R soluble domain (mutant) + FAD
1ib0 - rb5R soluble domain + FAD + NAD
2eix - b5R + FAD - Physarum polycephalum

References

  1. Bando S, Takano T, Yubisui T, Shirabe K, Takeshita M, Nakagawa A. Structure of human erythrocyte NADH-cytochrome b5 reductase. Acta Crystallogr D Biol Crystallogr. 2004 Nov;60(Pt 11):1929-34. Epub 2004, Oct 20. PMID:15502298 doi:10.1107/S0907444904020645
  2. Aalfs CM, Salieb-Beugelaar GB, Wanders RJ, Mannens MM, Wijburg FA. A case of methemoglobinemia type II due to NADH-cytochrome b5 reductase deficiency: determination of the molecular basis. Hum Mutat. 2000;16(1):18-22. doi:, 10.1002/1098-1004(200007)16:1<18::AID-HUMU4>3.0.CO;2-N. PMID:10874300 doi:<18::AID-HUMU4>3.0.CO;2-N http://dx.doi.org/10.1002/1098-1004(200007)16:1<18::AID-HUMU4>3.0.CO;2-N
  3. Sacco JC, Trepanier LA. Cytochrome b5 and NADH cytochrome b5 reductase: genotype-phenotype correlations for hydroxylamine reduction. Pharmacogenet Genomics. 2010 Jan;20(1):26-37. doi: 10.1097/FPC.0b013e3283343296. PMID:19997042 doi:http://dx.doi.org/10.1097/FPC.0b013e3283343296

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Michal Harel

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