1gus
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(New page: 200px<br /> <applet load="1gus" size="450" color="white" frame="true" align="right" spinBox="true" caption="1gus, resolution 1.80Å" /> '''MOPII FROM CLOSTRID...)
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Revision as of 15:30, 29 October 2007
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MOPII FROM CLOSTRIDIUM PASTEURIANUM (APO1)
Overview
MopII from Clostridium pasteurianum is a molbindin family member. These, proteins may serve as intracellular storage facilities for molybdate, which they bind with high specificity. High resolution structures of MopII, in a number of states, including the first structure of an apo-molbindin, together with calorimetric data, allow us to describe ligand binding and, provide support for the proposed storage function of the protein. MopII, assembles as a trimer of dimers and binds eight oxyanions at two types of, binding sites located at intersubunit interfaces. Two type 1 sites are on, the molecular 3-fold axis and three pairs of type 2 sites occur on the, molecular 2-fold axes. The hexamer is largely unaffected by the binding of, ligand. Molybdate is admitted to the otherwise inaccessible ... [(full description)]
About this Structure
1GUS is a [Single protein] structure of sequence from [Clostridium pasteurianum] with MG and CL as [ligands]. Full crystallographic information is available from [OCA].
Reference
Passive acquisition of ligand by the MopII molbindin from Clostridium pasteurianum: structures of apo and oxyanion-bound forms., Schuttelkopf AW, Harrison JA, Boxer DH, Hunter WN, J Biol Chem. 2002 Apr 26;277(17):15013-20. Epub 2002 Feb 8. PMID:11836258
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