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Sialidase

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== Function ==
== Function ==
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'''Sialidase''' is a neuraminidase which cleaves terminal sialic acid from a variety of natural substances <ref>PMID:12374200</ref>. '''Trans-sialidase''' is a modified sialidase which has transglycosidase activity and transfers sialic acid from host glycoconjugates to β-galactose on a parasite surface<ref>PMID:15588836</ref>, <ref>PMID:8405811</ref>.
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'''Sialidase''' is a neuraminidase which cleaves terminal sialic acid from a variety of natural substances <ref>PMID:12374200</ref>. For '''Trans-sialidase''' see [[Neuraminidase]].
== Disease ==
== Disease ==

Revision as of 07:45, 7 November 2018

Caption for this structure

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3D structures of salidase

Updated on 07-November-2018

References

  1. ↑ Monti E, Preti A, Venerando B, Borsani G. Recent development in mammalian sialidase molecular biology. Neurochem Res. 2002 Aug;27(7-8):649-63. PMID:12374200
  2. ↑ Miller BR 3rd, Roitberg AE. Trypanosoma cruzi trans-sialidase as a drug target against Chagas disease (American trypanosomiasis). Future Med Chem. 2013 Oct;5(15):1889-900. doi: 10.4155/fmc.13.129. PMID:24144418 doi:http://dx.doi.org/10.4155/fmc.13.129

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Jaime Prilusky

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