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6bhb

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'''Unreleased structure'''
 
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The entry 6bhb is ON HOLD until Paper Publication
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==Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 2-aminopyrimidin-5-ol==
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<StructureSection load='6bhb' size='340' side='right' caption='[[6bhb]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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Authors: Faheem, M., Neto, J.B., Collins, P., Pearce, N.M., Valadares, N.F., Bird, L., Pereira, H.M., Delft, F.V., Barbosa, J.A.R.G.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6bhb]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BHB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BHB FirstGlance]. <br>
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Description: Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 2-aminopyrimidin-5-ol
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=DS1:2-aminopyrimidin-5-ol'>DS1</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>
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[[Category: Pearce, N.M]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5cxq|5cxq]]</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bhb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bhb OCA], [http://pdbe.org/6bhb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bhb RCSB], [http://www.ebi.ac.uk/pdbsum/6bhb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bhb ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/A0A0U3AGT1_SCHMA A0A0U3AGT1_SCHMA]] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.[PIRNR:PIRNR000477]
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__TOC__
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</StructureSection>
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[[Category: Purine-nucleoside phosphorylase]]
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[[Category: Barbosa, J A.R G]]
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[[Category: Bird, L]]
[[Category: Collins, P]]
[[Category: Collins, P]]
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[[Category: Pereira, H.M]]
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[[Category: Delft, F V]]
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[[Category: Barbosa, J.A.R.G]]
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[[Category: Bird, L]]
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[[Category: Faheem, M]]
[[Category: Faheem, M]]
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[[Category: Delft, F.V]]
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[[Category: Neto, J B]]
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[[Category: Neto, J.B]]
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[[Category: Pearce, N M]]
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[[Category: Valadares, N.F]]
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[[Category: Pereira, H M]]
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[[Category: Valadares, N F]]
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[[Category: Purine nucleoside phosphorylase]]
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[[Category: Transferase]]

Revision as of 12:11, 7 November 2018

Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 2-aminopyrimidin-5-ol

6bhb, resolution 2.00Å

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