6his
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Mouse serotonin 5-HT3 receptor, tropisetron-bound, T conformation== | |
| - | + | <StructureSection load='6his' size='340' side='right' caption='[[6his]], [[Resolution|resolution]] 4.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6his]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HIS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HIS FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=TKT:(3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL+1H-INDOLE-3-CARBOXYLATE'>TKT</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6his FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6his OCA], [http://pdbe.org/6his PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6his RCSB], [http://www.ebi.ac.uk/pdbsum/6his PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6his ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/5HT3A_MOUSE 5HT3A_MOUSE]] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Neumann, E]] | ||
| + | [[Category: Nury, H]] | ||
| + | [[Category: Polovinkin, L]] | ||
| + | [[Category: Schoehn, G]] | ||
| + | [[Category: Ion channel]] | ||
| + | [[Category: Membrane protein]] | ||
| + | [[Category: Pentameric ligand-gated channel]] | ||
| + | [[Category: Serotonin receptor]] | ||
Revision as of 12:22, 7 November 2018
Mouse serotonin 5-HT3 receptor, tropisetron-bound, T conformation
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