This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


Thiamin phosphate synthase

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: <StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> == Function == '''Thiamin phosphate synthase''' (TPS) catalyzes the synthesisd of 4-...)
Line 1: Line 1:
-
 
+
<StructureSection load='2tps' size='340' side='right' caption='Caption for this structure' scene=''>
-
<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''>
+
== Function ==
== Function ==
-
'''Thiamin phosphate synthase''' (TPS) catalyzes the synthesisd of 4-methyl-5 (β-hydroxyethyl)thiazole phosphate (thz-P) amd 4-amino-5(hydroxymethyl)-2-methylpyrimidine pyrophosphate (HMP-PP) to produce thiamin phosphate and pyrophosphate<ref>PMID:11513588</ref>
+
'''Thiamin phosphate synthase''' (TPS) catalyzes the synthesisd of 4-methyl-5 (β-hydroxyethyl)thiazole phosphate (Thz-P) amd 4-amino-5(hydroxymethyl)-2-methylpyrimidine pyrophosphate (HMP-PP) to produce thiamin phosphate and pyrophosphate<ref>PMID:11513588</ref>
== Disease ==
== Disease ==
Line 14: Line 13:
</StructureSection>
</StructureSection>
-
[[1g4e]], [[3o16]] - BsTPS (mutant) - Bacillus subtilis<br />
+
==3D structures of thiamin phosphate synthase==
-
[[1g4p]] - BsTPS (mutant) + pyrimidine derivative<br />
+
 
-
[[1g67]], [[1g69]], [[1g6c]] - BsTPS (mutant) + pyrimidine derivative + PPi<br />
+
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 +
 
 +
[[1g4e]], [[3o16]] - BsTPS (mutant) - ''Bacillus subtilis''<br />
 +
[[1g4p]] - BsTPS (mutant) + Thz-P<br />
 +
[[1g67]], [[1g69]], [[1g6c]] - BsTPS (mutant) + Thz-P + PPi<br />
[[1g4t]] - BsTPS + thiamine phosphate derivative<br />
[[1g4t]] - BsTPS + thiamine phosphate derivative<br />
[[1g4s]] - BsTPS (mutant) + thiamine phosphate derivative<br />
[[1g4s]] - BsTPS (mutant) + thiamine phosphate derivative<br />
-
[[2tps]] - BsTPS + thiamine phosphate derivative + PPi<br />
+
[[2tps]] - BsTPS + thiamine phosphate + PPi<br />
[[3o15]] - BsTPS + thiazole phosphate derivative + PPi<br />
[[3o15]] - BsTPS + thiazole phosphate derivative + PPi<br />
-
[[3o63]] - TPS + Pi - Mycobacterium tuberculosis<br />
+
[[3o63]] - TPS + Pi - ''Mycobacterium tuberculosis''<br />
-
[[1xi3]] - TPS - Pyrococcus furiosus<br />
+
[[1xi3]] - TPS - ''Pyrococcus furiosus''<br />
== References ==
== References ==
<references/>
<references/>
 +
 +
[[Category:Topic Page]]

Revision as of 07:43, 12 November 2018

Caption for this structure

Drag the structure with the mouse to rotate

3D structures of thiamin phosphate synthase

Updated on 12-November-2018

1g4e, 3o16 - BsTPS (mutant) - Bacillus subtilis
1g4p - BsTPS (mutant) + Thz-P
1g67, 1g69, 1g6c - BsTPS (mutant) + Thz-P + PPi
1g4t - BsTPS + thiamine phosphate derivative
1g4s - BsTPS (mutant) + thiamine phosphate derivative
2tps - BsTPS + thiamine phosphate + PPi
3o15 - BsTPS + thiazole phosphate derivative + PPi
3o63 - TPS + Pi - Mycobacterium tuberculosis
1xi3 - TPS - Pyrococcus furiosus

References

  1. ↑ Reddick JJ, Nicewonger R, Begley TP. Mechanistic studies on thiamin phosphate synthase: evidence for a dissociative mechanism. Biochemistry. 2001 Aug 28;40(34):10095-102. PMID:11513588

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel

Retrieved from "http://52.214.119.220/wiki/index.php/Thiamin_phosphate_synthase"
Personal tools