RNA-guided pseudouridine synthase
From Proteopedia
(Difference between revisions)
(New page: {{Stub}] H/ACA ribonucleproteins that use RNAs to guide pseudouridine formation * 3hay - the full complex with substrate RNA (archaea ''Pyrococcus furiosus'') * [[3h...) |
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| - | H/ACA | + | <StructureSection load='3hay' size='400' side='right' caption=' 'Pyrococcus furiosus RNA-guided Pseudouridine synthase in complex with substrate [[3hay]]' scene='' pspeed='8'> |
| + | == Function == | ||
| + | H/ACA ribonucleoproteins that use RNAs to guide [[pseudouridine|pseudouridine]] formation. | ||
| - | * [[3hay]] - the full complex with substrate RNA ( | + | |
| - | * [[3hjw]] - the Cbf5-L7Ae-Nop10-guide RNA-substrate RNA complex ( | + | ==Beyond synthases== |
| - | * [[2hvy]] - Cbf5-Gar1-L7Ae-Nop10-guide RNA complex ( | + | |
| - | * [[3hjy]] - the Cbf5-Nop10-guide RNA-substrate RNA complex ( | + | Interestingly, there are clearly-related complexes do not seem to guide pseudouridine formation. Similar complexes with the same proteins and similar RNAs are also known to be involved in cleavage of rRNA or stabilizing the ends of non-coding RNAs. Although they share even the same catalytic protein, the do not some to catalyze the reaction as with other substrates. |
| - | * [[2rfk]] - Cbf5-Gar1-Nop10-guide RNA-substrate RNA complex ( | + | |
| - | * [[3hax]] - Cbf5-L7Ae-Nop10-guide RNA-substrate RNA complex ( | + | |
| - | * [[2apo]] - Cbf5-Nop10 complex ( | + | ==Structures of RNA-guided pseudoridine synthase== |
| - | * [[2aus]] - Cbf5-Nop10 complex ( | + | |
| - | * [[3hay]] - the full complex with substrate RNA ( | + | Eukaryotic |
| - | * [[2ey4]] - Cbf5-Gar1-Nop10 complex ( | + | * [[Cbf5-Nop10-Gar1]] complex (eukaryote Saccharomyces cerevisiae]] |
| + | |||
| + | Archaeal | ||
| + | ** [[3hay]] - the full complex with substrate RNA ( ''Pyrococcus furiosus'') | ||
| + | ** [[3hjw]] - the Cbf5-L7Ae-Nop10-guide RNA-substrate RNA complex (''Pyrococcus furiosus'') | ||
| + | ** [[2hvy]] - Cbf5-Gar1-L7Ae-Nop10-guide RNA complex (''Pyrococcus furiosus'') | ||
| + | ** [[3hjy]] - the Cbf5-Nop10-guide RNA-substrate RNA complex (''Pyrococcus furiosus'') | ||
| + | ** [[2rfk]] - Cbf5-Gar1-Nop10-guide RNA-substrate RNA complex (''Pyrococcus furiosus'') | ||
| + | ** [[3hax]] - Cbf5-L7Ae-Nop10-guide RNA-substrate RNA complex (''Pyrococcus furiosus'') | ||
| + | ** [[2apo]] - Cbf5-Nop10 complex (''Methanococcus jannaschii'') | ||
| + | ** [[2aus]] - Cbf5-Nop10 complex (''Pyrococcus abyssi'') | ||
| + | ** [[3hay]] - the full complex with substrate RNA (''Pyrococcus furiosus'') | ||
| + | * [[2ey4]] - Cbf5-Gar1-Nop10 complex (''Pyrococcus furiosus'') | ||
Revision as of 17:42, 13 November 2018
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