5yr5
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Human methionine aminopeptidase type 1b (F309L mutant) in complex with Ovalicin== | |
| - | + | <StructureSection load='5yr5' size='340' side='right' caption='[[5yr5]], [[Resolution|resolution]] 1.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5yr5]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YR5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YR5 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OVA:3,4-DIHYDROXY-2-METHOXY-4-METHYL-3-[2-METHYL-3-(3-METHYL-BUT-2-ENYL)+-OXIRANYL]-CYCLOHEXANONE'>OVA</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ykp|5ykp]], [[5yr4|5yr4]], [[5yr6|5yr6]]</td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionyl_aminopeptidase Methionyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.18 3.4.11.18] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yr5 OCA], [http://pdbe.org/5yr5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yr5 RCSB], [http://www.ebi.ac.uk/pdbsum/5yr5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yr5 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MAP11_HUMAN MAP11_HUMAN]] Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Required for normal progression through the cell cycle.[HAMAP-Rule:MF_03174]<ref>PMID:16274222</ref> <ref>PMID:17114291</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Methionyl aminopeptidase]] | ||
[[Category: Addlagatta, A]] | [[Category: Addlagatta, A]] | ||
| + | [[Category: Arya, T]] | ||
[[Category: Pillalamarri, V]] | [[Category: Pillalamarri, V]] | ||
| - | [[Category: | + | [[Category: Hydrolase]] |
| + | [[Category: Metal binding protein]] | ||
| + | [[Category: Methionine aminopeptidase]] | ||
Revision as of 08:04, 14 November 2018
Human methionine aminopeptidase type 1b (F309L mutant) in complex with Ovalicin
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