6bki

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'''Unreleased structure'''
 
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The entry 6bki is ON HOLD until Paper Publication
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==Crystal structure of T101A variant mouse cathepsin K at 2.94 Angstrom resolution.==
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<StructureSection load='6bki' size='340' side='right' caption='[[6bki]], [[Resolution|resolution]] 2.94&Aring;' scene=''>
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Authors: Law, S., Aguda, A., Brayer, G., Bromme, D.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6bki]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BKI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BKI FirstGlance]. <br>
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Description: Crystal structure of T101A variant mouse cathepsin K at 2.94 Angstrom resolution.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_K Cathepsin K], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.38 3.4.22.38] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bki OCA], [http://pdbe.org/6bki PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bki RCSB], [http://www.ebi.ac.uk/pdbsum/6bki PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bki ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/CATK_MOUSE CATK_MOUSE]] Closely involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation (By similarity).
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__TOC__
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</StructureSection>
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[[Category: Cathepsin K]]
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[[Category: Aguda, A]]
[[Category: Brayer, G]]
[[Category: Brayer, G]]
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[[Category: Bromme, D]]
[[Category: Law, S]]
[[Category: Law, S]]
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[[Category: Bromme, D]]
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[[Category: Cathepsin k]]
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[[Category: Aguda, A]]
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[[Category: Hydrolase]]
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[[Category: Mouse]]

Revision as of 08:06, 14 November 2018

Crystal structure of T101A variant mouse cathepsin K at 2.94 Angstrom resolution.

6bki, resolution 2.94Å

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