This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6bki
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of T101A variant mouse cathepsin K at 2.94 Angstrom resolution.== | |
| - | + | <StructureSection load='6bki' size='340' side='right' caption='[[6bki]], [[Resolution|resolution]] 2.94Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6bki]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BKI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BKI FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_K Cathepsin K], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.38 3.4.22.38] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bki OCA], [http://pdbe.org/6bki PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bki RCSB], [http://www.ebi.ac.uk/pdbsum/6bki PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bki ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CATK_MOUSE CATK_MOUSE]] Closely involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Cathepsin K]] | ||
| + | [[Category: Aguda, A]] | ||
[[Category: Brayer, G]] | [[Category: Brayer, G]] | ||
| + | [[Category: Bromme, D]] | ||
[[Category: Law, S]] | [[Category: Law, S]] | ||
| - | [[Category: | + | [[Category: Cathepsin k]] |
| - | [[Category: | + | [[Category: Hydrolase]] |
| + | [[Category: Mouse]] | ||
Revision as of 08:06, 14 November 2018
Crystal structure of T101A variant mouse cathepsin K at 2.94 Angstrom resolution.
| |||||||||||
Categories: Cathepsin K | Aguda, A | Brayer, G | Bromme, D | Law, S | Cathepsin k | Hydrolase | Mouse
