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6f6j

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'''Unreleased structure'''
 
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The entry 6f6j is ON HOLD until Paper Publication
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==Crystal structure of the Fe(II)/alpha-ketoglutarate dependent dioxygenase KDO1 with Fe(II)/succinate/(3S)-3-hydroxy-L-lysine==
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<StructureSection load='6f6j' size='340' side='right' caption='[[6f6j]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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Authors: Isabet, T., Stura, E.A., Legrand, P., Zaparucha, A., Bastard, K.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6f6j]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F6J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6F6J FirstGlance]. <br>
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Description: Crystal structure of the Fe(II)/alpha-ketoglutarate dependent dioxygenase KDO1 with Fe(II)/succinate/(3S)-3-hydroxy-L-lysine
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CUW:(2~{S},3~{R})-2,6-bis(azanyl)-3-oxidanyl-hexanoic+acid'>CUW</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6f6j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f6j OCA], [http://pdbe.org/6f6j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6f6j RCSB], [http://www.ebi.ac.uk/pdbsum/6f6j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6f6j ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/LYS3O_CATAD LYS3O_CATAD]] Alpha-ketoglutarate-dependent dioxygenase that in vitro catalyzes the regio- and stereoselective hydroxylation of L-lysine, leading to (3S)-3-hydroxy-L-lysine. Can also use (5R)-5-hydroxy-L-lysine as substrate, but neither D-lysine nor L-ornithine.[REFERENCE:2]
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__TOC__
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</StructureSection>
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[[Category: Bastard, K]]
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[[Category: Isabet, T]]
[[Category: Legrand, P]]
[[Category: Legrand, P]]
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[[Category: Isabet, T]]
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[[Category: Stura, E A]]
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[[Category: Bastard, K]]
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[[Category: Zaparucha, A]]
[[Category: Zaparucha, A]]
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[[Category: Stura, E.A]]
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[[Category: Dioxygenase]]
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[[Category: Enzyme]]
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[[Category: Feii alphakg form]]
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[[Category: Oxidoreductase]]
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[[Category: Oxydoreductase]]

Revision as of 08:18, 14 November 2018

Crystal structure of the Fe(II)/alpha-ketoglutarate dependent dioxygenase KDO1 with Fe(II)/succinate/(3S)-3-hydroxy-L-lysine

6f6j, resolution 2.00Å

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