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3dzi
From Proteopedia
(Difference between revisions)
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==Crystal structure of human CD38 extracellular domain, ribose-5'-phosphate intermediate/GTP complex== | ==Crystal structure of human CD38 extracellular domain, ribose-5'-phosphate intermediate/GTP complex== | ||
<StructureSection load='3dzi' size='340' side='right' caption='[[3dzi]], [[Resolution|resolution]] 1.73Å' scene=''> | <StructureSection load='3dzi' size='340' side='right' caption='[[3dzi]], [[Resolution|resolution]] 1.73Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3dzi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DZI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3DZI FirstGlance]. <br> | <table><tr><td colspan='2'>[[3dzi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DZI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3DZI FirstGlance]. <br> | ||
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=N:ANY+5-MONOPHOSPHATE+NUCLEOTIDE'>N</scene>, <scene name='pdbligand=RGT:2-AMINO-9-{5-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}PHOSPHORYL]-BETA-D-RIBOFURANOSYL}-9H-PURIN-6-YL+5-O-PHOSPHONO-BETA-D-RIBOFURANOSIDE'>RGT | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=N:ANY+5-MONOPHOSPHATE+NUCLEOTIDE'>N</scene>, <scene name='pdbligand=RGT:2-AMINO-9-{5-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}PHOSPHORYL]-BETA-D-RIBOFURANOSYL}-9H-PURIN-6-YL+5-O-PHOSPHONO-BETA-D-RIBOFURANOSIDE'>RGT</scene></td></tr> |
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3dzf|3dzf]], [[3dzg|3dzg]], [[3dzh|3dzh]], [[3dzj|3dzj]], [[3dzk|3dzk]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3dzf|3dzf]], [[3dzg|3dzg]], [[3dzh|3dzh]], [[3dzj|3dzj]], [[3dzk|3dzk]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CD38 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CD38 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_nucleosidase NAD(+) nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.5 3.2.2.5] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_nucleosidase NAD(+) nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.5 3.2.2.5] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dzi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dzi OCA], [http://pdbe.org/3dzi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3dzi RCSB], [http://www.ebi.ac.uk/pdbsum/3dzi PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dzi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dzi OCA], [http://pdbe.org/3dzi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3dzi RCSB], [http://www.ebi.ac.uk/pdbsum/3dzi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3dzi ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dz/3dzi_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dz/3dzi_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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[[Category: Liu, Q]] | [[Category: Liu, Q]] | ||
[[Category: Alpha bundle]] | [[Category: Alpha bundle]] | ||
| + | [[Category: Alternative splicing]] | ||
[[Category: Beta sheet]] | [[Category: Beta sheet]] | ||
[[Category: Diabetes mellitus]] | [[Category: Diabetes mellitus]] | ||
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[[Category: Nad]] | [[Category: Nad]] | ||
[[Category: Noncovalent intermediate]] | [[Category: Noncovalent intermediate]] | ||
| + | [[Category: Polymorphism]] | ||
[[Category: R5p-gtp adduct]] | [[Category: R5p-gtp adduct]] | ||
[[Category: Receptor]] | [[Category: Receptor]] | ||
[[Category: Signal-anchor]] | [[Category: Signal-anchor]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
Revision as of 09:16, 14 November 2018
Crystal structure of human CD38 extracellular domain, ribose-5'-phosphate intermediate/GTP complex
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Categories: Human | Graeff, R | Hao, Q | Jiang, H | Kriksunov, I A | Lee, H C | Lin, H | Liu, Q | Alpha bundle | Alternative splicing | Beta sheet | Diabetes mellitus | Glycoprotein | Gtp complex | Hydrolase | Membrane | Nad | Noncovalent intermediate | Polymorphism | R5p-gtp adduct | Receptor | Signal-anchor | Transmembrane
