3d8w
From Proteopedia
(Difference between revisions)
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==Use of a carbonic Anhydrase II, IX Active-site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties== | ==Use of a carbonic Anhydrase II, IX Active-site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties== | ||
<StructureSection load='3d8w' size='340' side='right' caption='[[3d8w]], [[Resolution|resolution]] 1.70Å' scene=''> | <StructureSection load='3d8w' size='340' side='right' caption='[[3d8w]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D8W:5-[(PHENYLSULFONYL)AMINO]-1,3,4-THIADIAZOLE-2-SULFONAMIDE'>D8W</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D8W:5-[(PHENYLSULFONYL)AMINO]-1,3,4-THIADIAZOLE-2-SULFONAMIDE'>D8W</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] </span></td></tr> | ||
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3d8w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d8w OCA], [http://pdbe.org/3d8w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3d8w RCSB], [http://www.ebi.ac.uk/pdbsum/3d8w PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3d8w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d8w OCA], [http://pdbe.org/3d8w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3d8w RCSB], [http://www.ebi.ac.uk/pdbsum/3d8w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3d8w ProSAT]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
- | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d8/3d8w_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d8/3d8w_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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[[Category: Mckenna, R]] | [[Category: Mckenna, R]] | ||
[[Category: Sippel, K H]] | [[Category: Sippel, K H]] | ||
+ | [[Category: Acetylation]] | ||
[[Category: Anti-cancer]] | [[Category: Anti-cancer]] | ||
[[Category: Benzolamide]] | [[Category: Benzolamide]] | ||
[[Category: Carbonic anhydrase ii]] | [[Category: Carbonic anhydrase ii]] | ||
+ | [[Category: Cytoplasm]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
[[Category: Lyase]] | [[Category: Lyase]] | ||
[[Category: Metal-binding]] | [[Category: Metal-binding]] | ||
+ | [[Category: Polymorphism]] | ||
+ | [[Category: Zinc]] |
Revision as of 09:47, 14 November 2018
Use of a carbonic Anhydrase II, IX Active-site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties
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