Sandbox Reserved 1458

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You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
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== Function == The organism the PLpro is from is Coronaviruses. IBV PLpro performs deubiquitination with catalytic efficiencies that are different from other PLpros. Papain-like protease (PLpro) of coronaviruses (CoVs) carries out proteolytic maturation of non-structural proteins that play a role in replication of the virus and performs deubiquitination of host cell factors to scuttle antiviral responses. The substrates and products are
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== Function ==
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The organism the PLpro is from is Coronaviruses. IBV PLpro performs deubiquitination with catalytic efficiencies that are different from other PLpros. Papain-like protease (PLpro) of coronaviruses (CoVs) carries out proteolytic maturation of non-structural proteins that play a role in replication of the virus and performs deubiquitination of host cell factors to scuttle antiviral responses. The substrates and products are
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== Disease == . A disease associated with the PLpro protein is avian infectious bronchitis in poultry, The protein helps out with scuttling antiviral responses and when this protein is working it stops the host(chicken) from being able to keep the virus from replicating.
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== Disease ==
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A disease associated with the PLpro protein is avian infectious bronchitis in poultry, The protein helps out with scuttling antiviral responses and when this protein is working it stops the host(chicken) from being able to keep the virus from replicating.
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== Relevance == The results can be used to develop antivirals for the chickens and help save economic loss every year in the poultry industry.
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== Relevance ==
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The results can be used to develop antivirals for the chickens and help save economic loss every year in the poultry industry.
== Structural highlights ==
== Structural highlights ==

Revision as of 01:22, 15 November 2018

This Sandbox is Reserved from October 22, 2018 through April 30, 2019 for use in the course Biochemistry taught by Bonnie Hall at the Grand View University, Des Moines, IA USA. This reservation includes Sandbox Reserved 1456 through Sandbox Reserved 1470.
To get started:
  • Click the edit this page tab at the top. Save the page after each step, then edit it again.
  • Click the 3D button (when editing, above the wikitext box) to insert Jmol.
  • show the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
  • Add a description of your scene. Use the buttons above the wikitext box for bold, italics, links, headlines, etc.

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References

  1. ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
  2. ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
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