Syntaxin

From Proteopedia

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Revision as of 09:41, 25 November 2018

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spinqualitylabelsall models Caption for this structure Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Contents 1 Function 2 Disease 3 Relevance 4 Structural highlights Function Syntaxin (Stx) are membrane-integrated proteins that are instrumental in exocytosis of vescicles. Sts-1 is essential in the fusion machinery in the brain. It forms a 4-helical bundle comples with proteins SNAP-25 and VAMP2d which drives fusion of vescicles with the plasma membrane[1]. Disease Relevance Structural highlights

3D structures of syntaxin

Updated on 25-November-2018

References

1. ↑ Hussain S, Ringsevjen H, Egbenya DL, Skjervold TL, Davanger S. SNARE Protein Syntaxin-1 Colocalizes Closely with NMDA Receptor Subunit NR2B in Postsynaptic Spines in the Hippocampus. Front Mol Neurosci. 2016 Feb 5;9:10. doi: 10.3389/fnmol.2016.00010. eCollection, 2016. PMID:26903802 doi:http://dx.doi.org/10.3389/fnmol.2016.00010