6ioz
From Proteopedia
(Difference between revisions)
m (Protected "6ioz" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Structural insights of idursulfase beta== | |
| - | + | <StructureSection load='6ioz' size='340' side='right' caption='[[6ioz]], [[Resolution|resolution]] 3.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6ioz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IOZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IOZ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALS:(3S)-3-(SULFOOXY)-L-SERINE'>ALS</scene></td></tr> |
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">IDS, SIDS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Iduronate-2-sulfatase Iduronate-2-sulfatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.6.13 3.1.6.13] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ioz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ioz OCA], [http://pdbe.org/6ioz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ioz RCSB], [http://www.ebi.ac.uk/pdbsum/6ioz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ioz ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/IDS_HUMAN IDS_HUMAN]] Mucopolysaccharidosis type 2, attenuated form;Mucopolysaccharidosis type 2, severe form. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/IDS_HUMAN IDS_HUMAN]] Required for the lysosomal degradation of heparan sulfate and dermatan sulfate. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Iduronate-2-sulfatase]] | ||
| + | [[Category: Hong, J]] | ||
| + | [[Category: Kim, D]] | ||
[[Category: Kim, H]] | [[Category: Kim, H]] | ||
| - | [[Category: Hong, J]] | ||
[[Category: Lee, K]] | [[Category: Lee, K]] | ||
| + | [[Category: Oh, B H]] | ||
[[Category: Seo, J]] | [[Category: Seo, J]] | ||
| - | [[Category: | + | [[Category: Alpha-l-iduronate sulfate sulfatase]] |
| - | [[Category: | + | [[Category: Hydrolase]] |
| + | [[Category: Iduronate 2-sulfatase 14kda chain]] | ||
| + | [[Category: Iduronate 2-sulfatase 42kda chain]] | ||
| + | [[Category: Idursulfase beta]] | ||
Revision as of 20:35, 2 December 2018
Structural insights of idursulfase beta
| |||||||||||
