3ekr

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==Dihydroxylphenyl amides as inhibitors of the Hsp90 molecular chaperone==
==Dihydroxylphenyl amides as inhibitors of the Hsp90 molecular chaperone==
<StructureSection load='3ekr' size='340' side='right' caption='[[3ekr]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='3ekr' size='340' side='right' caption='[[3ekr]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3eko|3eko]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3eko|3eko]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HSP90AA1, HSP90A, HSPC1, HSPCA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HSP90AA1, HSP90A, HSPC1, HSPCA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ekr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ekr OCA], [http://pdbe.org/3ekr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ekr RCSB], [http://www.ebi.ac.uk/pdbsum/3ekr PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ekr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ekr OCA], [http://pdbe.org/3ekr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ekr RCSB], [http://www.ebi.ac.uk/pdbsum/3ekr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ekr ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ek/3ekr_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ek/3ekr_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Human]]
[[Category: Human]]
[[Category: Gajiwala, K S]]
[[Category: Gajiwala, K S]]
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[[Category: Alternative splicing]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Chaperone]]
[[Category: Chaperone]]
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[[Category: Cytoplasm]]
[[Category: Hsp90 inhibitor]]
[[Category: Hsp90 inhibitor]]
[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Stress response]]
[[Category: Stress response]]

Revision as of 21:34, 2 December 2018

Dihydroxylphenyl amides as inhibitors of the Hsp90 molecular chaperone

3ekr, resolution 2.00Å

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