5ynm

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'''Unreleased structure'''
 
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The entry 5ynm is ON HOLD until Paper Publication
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==Crystal structure of MERS-CoV nsp16/nsp10 complex bound to SAM and m7GpppA==
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<StructureSection load='5ynm' size='340' side='right' caption='[[5ynm]], [[Resolution|resolution]] 1.68&Aring;' scene=''>
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Authors: Wei, S.M., Yang, L., Ke, Z.H., Guo, D.Y., Fan, C.P.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5ynm]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YNM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YNM FirstGlance]. <br>
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Description: Crystal structure of MERS-CoV nsp16/nsp10 complex bound to SAM and m7GpppA
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTA:P1-7-METHYLGUANOSINE-P3-ADENOSINE-5,5-TRIPHOSPHATE'>GTA</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ynm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ynm OCA], [http://pdbe.org/5ynm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ynm RCSB], [http://www.ebi.ac.uk/pdbsum/5ynm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ynm ProSAT]</span></td></tr>
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[[Category: Ke, Z.H]]
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</table>
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[[Category: Fan, C.P]]
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== Function ==
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[[http://www.uniprot.org/uniprot/K4LC41_9BETC K4LC41_9BETC]] Nsp7-nsp8 hexadecamer may possibly confer processivity to the polymerase, maybe by binding to dsRNA or by producing primers utilized by the latter (By similarity).[SAAS:SAAS014829_004_014545] Nsp9 is a ssRNA-binding protein (By similarity).[SAAS:SAAS014829_004_001449]
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__TOC__
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</StructureSection>
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[[Category: Fan, C P]]
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[[Category: Guo, D Y]]
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[[Category: Ke, Z H]]
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[[Category: Wei, S M]]
[[Category: Yang, L]]
[[Category: Yang, L]]
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[[Category: Guo, D.Y]]
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[[Category: Cofactor]]
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[[Category: Wei, S.M]]
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[[Category: Complex]]
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[[Category: Inhibitor]]
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[[Category: Transferase]]

Revision as of 06:28, 5 December 2018

Crystal structure of MERS-CoV nsp16/nsp10 complex bound to SAM and m7GpppA

5ynm, resolution 1.68Å

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