6i8l
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Spindlin1 in complex with the inhibitor TD001851a== | |
| - | + | <StructureSection load='6i8l' size='340' side='right' caption='[[6i8l]], [[Resolution|resolution]] 1.58Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6i8l]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I8L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6I8L FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=H7Q:5-(cyclopropylmethoxy)-6-[3-(1,3-dihydroisoindol-2-yl)propoxy]spiro[cyclopentane-1,3-indole]-2-amine'>H7Q</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6i8l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i8l OCA], [http://pdbe.org/6i8l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6i8l RCSB], [http://www.ebi.ac.uk/pdbsum/6i8l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6i8l ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SPIN1_HUMAN SPIN1_HUMAN]] May play a role in cell-cycle regulation during the transition from gamete to embryo (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Arrowsmith, C H]] | ||
| + | [[Category: Bountra, C]] | ||
| + | [[Category: Brennan, P E]] | ||
| + | [[Category: Edwards, A]] | ||
[[Category: Fagan, V]] | [[Category: Fagan, V]] | ||
| - | [[Category: Oppermann, U.C.T]] | ||
[[Category: Johansson, C]] | [[Category: Johansson, C]] | ||
| - | [[Category: Brennan, P.E]] | ||
| - | [[Category: Edwards, A]] | ||
[[Category: Krojer, T]] | [[Category: Krojer, T]] | ||
| - | [[Category: | + | [[Category: Oppermann, U C.T]] |
| - | [[Category: Sorrell, F | + | [[Category: Sorrell, F J]] |
| + | [[Category: Cell cycle]] | ||
| + | [[Category: Epigenetic]] | ||
| + | [[Category: Methyl-arginine]] | ||
| + | [[Category: Methyl-lysine]] | ||
| + | [[Category: Tudor domain]] | ||
Revision as of 06:48, 5 December 2018
Crystal structure of Spindlin1 in complex with the inhibitor TD001851a
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