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From Proteopedia
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== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/RGS3_HUMAN RGS3_HUMAN]] Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G-protein-mediated release of inositol phosphates and activation of MAP kinases.<ref>PMID:8602223</ref> <ref>PMID:9858594</ref> <ref>PMID:10749886</ref> <ref>PMID:11294858</ref> | [[http://www.uniprot.org/uniprot/RGS3_HUMAN RGS3_HUMAN]] Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G-protein-mediated release of inositol phosphates and activation of MAP kinases.<ref>PMID:8602223</ref> <ref>PMID:9858594</ref> <ref>PMID:10749886</ref> <ref>PMID:11294858</ref> | ||
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| + | ==See Also== | ||
| + | *[[Regulator of G protein signaling|Regulator of G protein signaling]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: Xiao, R]] | [[Category: Xiao, R]] | ||
[[Category: All beta-sheet fold]] | [[Category: All beta-sheet fold]] | ||
| + | [[Category: Alternative splicing]] | ||
[[Category: Cell membrane]] | [[Category: Cell membrane]] | ||
| + | [[Category: Cytoplasm]] | ||
[[Category: Membrane]] | [[Category: Membrane]] | ||
[[Category: Nesg]] | [[Category: Nesg]] | ||
Revision as of 07:16, 5 December 2018
Crystal structure of the C2 domain of the human regulator of G-protein signaling 3 isoform 6 (RGP3), Northeast Structural Genomics Consortium Target HR5550A
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Categories: Human | Acton, T B | Ciccosanti, C | Everett, J K | Foote, E L | Forouhar, F | Hunt, J F | Lew, S | Mao, L | Montelione, G T | Structural genomic | Nair, R | Rost, B | Seetharaman, J | Shastry, R | Tong, L | Xiao, R | All beta-sheet fold | Alternative splicing | Cell membrane | Cytoplasm | Membrane | Nesg | Nucleus | Phosphoprotein | PSI, Protein structure initiative | Signal transduction inhibitor | Signaling protein
