3g1r

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==Crystal structure of human liver 5beta-reductase (AKR1D1) in complex with NADP and Finasteride. Resolution 1.70 A==
==Crystal structure of human liver 5beta-reductase (AKR1D1) in complex with NADP and Finasteride. Resolution 1.70 A==
<StructureSection load='3g1r' size='340' side='right' caption='[[3g1r]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='3g1r' size='340' side='right' caption='[[3g1r]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AKR1D1, SRD5B1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AKR1D1, SRD5B1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Delta(4)-3-oxosteroid_5-beta-reductase Delta(4)-3-oxosteroid 5-beta-reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.3 1.3.1.3] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Delta(4)-3-oxosteroid_5-beta-reductase Delta(4)-3-oxosteroid 5-beta-reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.3 1.3.1.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g1r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g1r OCA], [http://pdbe.org/3g1r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3g1r RCSB], [http://www.ebi.ac.uk/pdbsum/3g1r PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g1r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g1r OCA], [http://pdbe.org/3g1r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3g1r RCSB], [http://www.ebi.ac.uk/pdbsum/3g1r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3g1r ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g1/3g1r_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g1/3g1r_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 3g1r" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3g1r" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Aldo-keto reductase|Aldo-keto reductase]]
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*[[Finasteride|Finasteride]]
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*[[User:Cody J Cubbage|User:Cody J Cubbage]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Penning, T M]]
[[Category: Penning, T M]]
[[Category: Bile acid catabolism]]
[[Category: Bile acid catabolism]]
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[[Category: Cytoplasm]]
[[Category: Disease mutation]]
[[Category: Disease mutation]]
[[Category: Finasteride complex]]
[[Category: Finasteride complex]]

Revision as of 07:58, 5 December 2018

Crystal structure of human liver 5beta-reductase (AKR1D1) in complex with NADP and Finasteride. Resolution 1.70 A

3g1r, resolution 1.70Å

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