This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3fc6
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| + | |||
==hRXRalpha & mLXRalpha with an indole Pharmacophore, SB786875== | ==hRXRalpha & mLXRalpha with an indole Pharmacophore, SB786875== | ||
<StructureSection load='3fc6' size='340' side='right' caption='[[3fc6]], [[Resolution|resolution]] 2.06Å' scene=''> | <StructureSection load='3fc6' size='340' side='right' caption='[[3fc6]], [[Resolution|resolution]] 2.06Å' scene=''> | ||
| Line 4: | Line 5: | ||
<table><tr><td colspan='2'>[[3fc6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FC6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FC6 FirstGlance]. <br> | <table><tr><td colspan='2'>[[3fc6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FC6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FC6 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LX2:[4-(3-{[2-CHLORO-3-(TRIFLUOROMETHYL)BENZYL](2,2-DIPHENYLETHYL)AMINO}PROPOXY)-1H-INDOL-1-YL]ACETIC+ACID'>LX2</scene>, <scene name='pdbligand=REA:RETINOIC+ACID'>REA</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LX2:[4-(3-{[2-CHLORO-3-(TRIFLUOROMETHYL)BENZYL](2,2-DIPHENYLETHYL)AMINO}PROPOXY)-1H-INDOL-1-YL]ACETIC+ACID'>LX2</scene>, <scene name='pdbligand=REA:RETINOIC+ACID'>REA</scene></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fc6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fc6 OCA], [http://pdbe.org/3fc6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fc6 RCSB], [http://www.ebi.ac.uk/pdbsum/3fc6 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fc6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fc6 OCA], [http://pdbe.org/3fc6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fc6 RCSB], [http://www.ebi.ac.uk/pdbsum/3fc6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3fc6 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| Line 12: | Line 13: | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fc/3fc6_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fc/3fc6_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
| Line 56: | Line 57: | ||
[[Category: Nuclear hormone receptor]] | [[Category: Nuclear hormone receptor]] | ||
[[Category: Nucleus]] | [[Category: Nucleus]] | ||
| + | [[Category: Polymorphism]] | ||
[[Category: Receptor]] | [[Category: Receptor]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
[[Category: Transcription regulation]] | [[Category: Transcription regulation]] | ||
| + | [[Category: Ubl conjugation]] | ||
| + | [[Category: Zinc]] | ||
[[Category: Zinc-finger]] | [[Category: Zinc-finger]] | ||
Revision as of 08:00, 5 December 2018
hRXRalpha & mLXRalpha with an indole Pharmacophore, SB786875
| |||||||||||
Categories: Homo sapiens | Mus musculus | Campobasso, N | Duraiswami, C | Evans, C | Frank, K | Hoang, T H | Jaye, M | Nord, M | Parks, D J | Smallwood, A | Thompson, S K | Washburn, D G | Webb, C L | Agonist | Dna-binding | Epoxycholesterol | Host-virus interaction | Liver x receptor | Metal-binding | Nuclear hormone receptor | Nucleus | Polymorphism | Receptor | Transcription | Transcription regulation | Ubl conjugation | Zinc | Zinc-finger
