Journal:Acta Cryst D:S2059798318017047
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<b>Molecular Tour</b><br> | <b>Molecular Tour</b><br> | ||
| - | The crystal structure of the N-acetylglucosamine-2-epimerase from ''Nostoc'' sp. KVJ10 (nAGE10) was obtained at a resolution of 1.7 Å. The nAGE10 monomer is folds as a (α/α)<sub>6</sub>-barrel in a manner similar to the previously published AGE structures. It is deposited in the PDB as | + | The crystal structure of the N-acetylglucosamine-2-epimerase from ''Nostoc'' sp. KVJ10 (nAGE10) was obtained at a resolution of 1.7 Å. The nAGE10 monomer is folds as a (α/α)<sub>6</sub>-barrel in a manner similar to the previously published AGE structures. It is deposited in the PDB as [[6f04]]. |
| - | The previously reported dimer organization, which involved the | + | The previously reported dimer organization, which involved the “back-to-back” assembly of the monomers, could not be found within the nAGE10 crystal. However, a “front-to-front” dimer generated by symmetry is present in all AGE structures with better parameters than the back-to-back organization. |
The new AGE dimer places the putative ATP binding site(s) at the interface between the monomers with consequences regarding its role in AGE activity. | The new AGE dimer places the putative ATP binding site(s) at the interface between the monomers with consequences regarding its role in AGE activity. | ||
Revision as of 09:47, 5 December 2018
http://proteopedia.org/w/Journal:Acta_Cryst_D:S2059798318017047
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