3b7o
From Proteopedia
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|PDB= 3b7o |SIZE=350|CAPTION= <scene name='initialview01'>3b7o</scene>, resolution 1.60Å | |PDB= 3b7o |SIZE=350|CAPTION= <scene name='initialview01'>3b7o</scene>, resolution 1.60Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand=MLT:MALATE ION'>MLT</scene> | + | |LIGAND= <scene name='pdbligand=MLT:MALATE+ION'>MLT</scene> |
| - | |ACTIVITY= [http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span> |
|GENE= PTPN11, PTP2C, SHPTP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |GENE= PTPN11, PTP2C, SHPTP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY=[[2shp|2SHP]] | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3b7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b7o OCA], [http://www.ebi.ac.uk/pdbsum/3b7o PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3b7o RCSB]</span> | ||
}} | }} | ||
'''Crystal structure of the human tyrosine phosphatase SHP2 (PTPN11) with an accessible active site''' | '''Crystal structure of the human tyrosine phosphatase SHP2 (PTPN11) with an accessible active site''' | ||
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| - | ==Disease== | ||
| - | Known diseases associated with this structure: Leopard syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176876 176876]], Leukemia, juvenile myelomonocytic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176876 176876]], Noonan syndrome 1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176876 176876]] | ||
==About this Structure== | ==About this Structure== | ||
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[[Category: Ugochukwu, E.]] | [[Category: Ugochukwu, E.]] | ||
[[Category: Weigelt, J.]] | [[Category: Weigelt, J.]] | ||
| - | [[Category: MLT]] | ||
[[Category: alternative splicing]] | [[Category: alternative splicing]] | ||
[[Category: cytoplasm]] | [[Category: cytoplasm]] | ||
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[[Category: tyrosine phosphatase]] | [[Category: tyrosine phosphatase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:23:51 2008'' |
Revision as of 02:23, 31 March 2008
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| , resolution 1.60Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | |||||||
| Gene: | PTPN11, PTP2C, SHPTP2 (Homo sapiens) | ||||||
| Activity: | Protein-tyrosine-phosphatase, with EC number 3.1.3.48 | ||||||
| Related: | 2SHP
| ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of the human tyrosine phosphatase SHP2 (PTPN11) with an accessible active site
About this Structure
3B7O is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Mon Mar 31 05:23:51 2008
Categories: Homo sapiens | Protein-tyrosine-phosphatase | Single protein | Arrowsmith, C H. | Barr, A. | Delft, F von. | Edwards, A M. | Elkins, J. | King, O. | Knapp, S. | Niesen, F. | Patel, A. | Pilka, E S. | SGC, Structural Genomics Consortium. | Salah, E. | Savitsky, P. | Ugochukwu, E. | Weigelt, J. | Alternative splicing | Cytoplasm | Deafness | Disease mutation | Hydrolase | Phosphorylation | Protein phosphatase | Ptpn11 | Sgc | Sh2 domain | Shp2 | Structural genomic | Structural genomics consortium | Tyrosine phosphatase
