6dhb
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the human TIM-3 with bound Calcium== | |
| - | + | <StructureSection load='6dhb' size='340' side='right' caption='[[6dhb]], [[Resolution|resolution]] 1.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6dhb]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DHB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DHB FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BEZ:BENZOIC+ACID'>BEZ</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dhb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dhb OCA], [http://pdbe.org/6dhb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dhb RCSB], [http://www.ebi.ac.uk/pdbsum/6dhb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dhb ProSAT]</span></td></tr> |
| - | [[ | + | </table> |
| - | [[ | + | == Function == |
| - | [[ | + | [[http://www.uniprot.org/uniprot/HAVR2_HUMAN HAVR2_HUMAN]] Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Receptor for LGALS9.<ref>PMID:14556005</ref> <ref>PMID:16286920</ref> |
| - | [[ | + | == References == |
| - | [ | + | <references/> |
| - | [[ | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| + | [[Category: Blumberg, R S]] | ||
[[Category: Bonsor, D]] | [[Category: Bonsor, D]] | ||
| + | [[Category: Gandhi, A K]] | ||
| + | [[Category: Huang, Y H]] | ||
| + | [[Category: Kim, W M]] | ||
[[Category: Kuchroo, V]] | [[Category: Kuchroo, V]] | ||
| + | [[Category: Petsko, G A]] | ||
| + | [[Category: Sun, Z Y]] | ||
| + | [[Category: Sundberg, E]] | ||
| + | [[Category: Immune system]] | ||
| + | [[Category: T cell immunoglobulin mucin-3 immunological tolerance]] | ||
Revision as of 06:44, 12 December 2018
Crystal structure of the human TIM-3 with bound Calcium
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