6du0

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'''Unreleased structure'''
 
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The entry 6du0 is ON HOLD until Paper Publication
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==Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain Y395L mutant==
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<StructureSection load='6du0' size='340' side='right' caption='[[6du0]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
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Authors: Salay, L.E., Chazin, W.J.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6du0]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DU0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DU0 FirstGlance]. <br>
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Description: Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain Y395L mutant
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6di2|6di2]], [[6di6|6di6]], [[6dtv|6dtv]], [[6dtz|6dtz]]</td></tr>
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[[Category: Chazin, W.J]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6du0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6du0 OCA], [http://pdbe.org/6du0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6du0 RCSB], [http://www.ebi.ac.uk/pdbsum/6du0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6du0 ProSAT]</span></td></tr>
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[[Category: Salay, L.E]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PRI2_YEAST PRI2_YEAST]] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. In a complex with DNA polymerase alpha (DNA polymerase alpha:primase) constitutes a replicative polymerase. Both primase components participate in formation of the active center, but the ATP-binding site is exclusively located on p48.
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__TOC__
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</StructureSection>
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[[Category: Chazin, W J]]
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[[Category: Salay, L E]]
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[[Category: Dna primase]]
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[[Category: Iron-sulfur cluster]]
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[[Category: P58]]
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[[Category: Regulatory subunit]]
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[[Category: Replication]]

Revision as of 06:44, 12 December 2018

Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain Y395L mutant

6du0, resolution 1.82Å

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