6f4v

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m (Protected "6f4v" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 6f4v is ON HOLD
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==Crystal structure of cleaved Kallistatin complexed with heparin at 1.8 Angstrom resolution==
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<StructureSection load='6f4v' size='340' side='right' caption='[[6f4v]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6f4v]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F4V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6F4V FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NTP:HEPARIN+PENTASACCHARIDE'>NTP</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6f4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f4v OCA], [http://pdbe.org/6f4v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6f4v RCSB], [http://www.ebi.ac.uk/pdbsum/6f4v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6f4v ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/KAIN_HUMAN KAIN_HUMAN]] Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.<ref>PMID:8227002</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Wei, Z]]
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[[Category: Zhou, A]]
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[[Category: Hydrolase]]
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[[Category: Inhibitor]]
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[[Category: Kellikrein]]
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[[Category: Serpin]]

Revision as of 06:48, 12 December 2018

Crystal structure of cleaved Kallistatin complexed with heparin at 1.8 Angstrom resolution

6f4v, resolution 1.80Å

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