6imf
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of TOXIN/ANTITOXIN complex== | |
- | + | <StructureSection load='6imf' size='340' side='right' caption='[[6imf]], [[Resolution|resolution]] 2.30Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[6imf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Protobothrops_flavoviridis Protobothrops flavoviridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IMF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IMF FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr> | |
- | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6imf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6imf OCA], [http://pdbe.org/6imf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6imf RCSB], [http://www.ebi.ac.uk/pdbsum/6imf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6imf ProSAT]</span></td></tr> |
- | [ | + | </table> |
- | [ | + | == Function == |
- | + | [[http://www.uniprot.org/uniprot/CRVP_PROFL CRVP_PROFL]] Blocks contraction of smooth muscle elicited by high potassium-induced depolarization (PubMed:12047379). May target voltage-gated calcium channels (Cav) on smooth muscle.<ref>PMID:12047379</ref> [[http://www.uniprot.org/uniprot/MSMB2_PROFL MSMB2_PROFL]] May serve as a self-defense protein against the toxic effects of the snake venom during accidental envenomation. Does not show inhibitory activity towards brevilysin H6. | |
- | [[ | + | == References == |
- | [[ | + | <references/> |
- | [[Category: | + | __TOC__ |
+ | </StructureSection> | ||
+ | [[Category: Protobothrops flavoviridis]] | ||
[[Category: Hu, Y]] | [[Category: Hu, Y]] | ||
[[Category: Kita, S]] | [[Category: Kita, S]] | ||
- | [[Category: | + | [[Category: Kurahara, L H]] |
+ | [[Category: Kuroki, K]] | ||
[[Category: Maenaka, K]] | [[Category: Maenaka, K]] | ||
- | [[Category: | + | [[Category: Matsubara, H]] |
+ | [[Category: Okabe, Y]] | ||
+ | [[Category: Ose, T]] | ||
+ | [[Category: Shioi, N]] | ||
[[Category: Shioi, S]] | [[Category: Shioi, S]] | ||
+ | [[Category: Tadokoro, T]] | ||
+ | [[Category: Terada, S]] | ||
+ | [[Category: Antitoxin]] | ||
+ | [[Category: Complex]] | ||
+ | [[Category: Toxin]] | ||
+ | [[Category: Toxin-antitoxin complex]] |
Revision as of 06:55, 12 December 2018
Crystal structure of TOXIN/ANTITOXIN complex
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Categories: Protobothrops flavoviridis | Hu, Y | Kita, S | Kurahara, L H | Kuroki, K | Maenaka, K | Matsubara, H | Okabe, Y | Ose, T | Shioi, N | Shioi, S | Tadokoro, T | Terada, S | Antitoxin | Complex | Toxin | Toxin-antitoxin complex