5yhl

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==Crystal structure of the clinically important GPCR in complex with functional antibody.==
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==Anomalous bromine signal of the human prostaglandin E receptor EP4 in complex with Fab and ONO-AE3-208-Br derivative==
<StructureSection load='5yhl' size='340' side='right' caption='[[5yhl]], [[Resolution|resolution]] 4.20&Aring;' scene=''>
<StructureSection load='5yhl' size='340' side='right' caption='[[5yhl]], [[Resolution|resolution]] 4.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5yhl]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YHL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YHL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5yhl]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YHL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YHL FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8VL:4-[2-[[(2R)-2-(4-bromanylnaphthalen-1-yl)propanoyl]amino]-4-cyano-phenyl]butanoic+acid'>8VL</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8VL:4-[2-[[(2R)-2-(4-bromanylnaphthalen-1-yl)propanoyl]amino]-4-cyano-phenyl]butanoic+acid'>8VL</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5wv2|5wv2]], [[5yfi|5yfi]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5wv2|5wv2]], [[5yfi|5yfi]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTGER4, PTGER2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yhl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yhl OCA], [http://pdbe.org/5yhl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yhl RCSB], [http://www.ebi.ac.uk/pdbsum/5yhl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yhl ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yhl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yhl OCA], [http://pdbe.org/5yhl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yhl RCSB], [http://www.ebi.ac.uk/pdbsum/5yhl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yhl ProSAT]</span></td></tr>
</table>
</table>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Lk3 transgenic mice]]
[[Category: Horita, S]]
[[Category: Horita, S]]
[[Category: Iwata, S]]
[[Category: Iwata, S]]

Revision as of 07:06, 12 December 2018

Anomalous bromine signal of the human prostaglandin E receptor EP4 in complex with Fab and ONO-AE3-208-Br derivative

5yhl, resolution 4.20Å

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