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5ywy

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==Crystal structure of the clinically important GPCR in complex with functional antibody.==
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==Crystal structure of the human prostaglandin E receptor EP4 in complex with Fab and ONO-AE3-208==
<StructureSection load='5ywy' size='340' side='right' caption='[[5ywy]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
<StructureSection load='5ywy' size='340' side='right' caption='[[5ywy]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ywy]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YWY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YWY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ywy]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YWY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YWY FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7UR:4-[4-cyano-2-[[(2R)-2-(4-fluoranylnaphthalen-1-yl)propanoyl]amino]phenyl]butanoic+acid'>7UR</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7UR:4-[4-cyano-2-[[(2R)-2-(4-fluoranylnaphthalen-1-yl)propanoyl]amino]phenyl]butanoic+acid'>7UR</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTGER4, PTGER2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ywy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ywy OCA], [http://pdbe.org/5ywy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ywy RCSB], [http://www.ebi.ac.uk/pdbsum/5ywy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ywy ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ywy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ywy OCA], [http://pdbe.org/5ywy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ywy RCSB], [http://www.ebi.ac.uk/pdbsum/5ywy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ywy ProSAT]</span></td></tr>
</table>
</table>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Lk3 transgenic mice]]
[[Category: Horita, S]]
[[Category: Horita, S]]
[[Category: Iwata, S]]
[[Category: Iwata, S]]

Revision as of 07:06, 12 December 2018

Crystal structure of the human prostaglandin E receptor EP4 in complex with Fab and ONO-AE3-208

5ywy, resolution 3.20Å

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