5qhm
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with OX-145== | |
| - | + | <StructureSection load='5qhm' size='340' side='right' caption='[[5qhm]], [[Resolution|resolution]] 1.79Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5qhm]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QHM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QHM FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GQA:1-methyl-3-oxidanyl-pyridine-2-thione'>GQA</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qhm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qhm OCA], [http://pdbe.org/5qhm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qhm RCSB], [http://www.ebi.ac.uk/pdbsum/5qhm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qhm ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/FA83B_HUMAN FA83B_HUMAN]] Probable proto-oncogene that functions in the epidermal growth factor receptor/EGFR signaling pathway. May activate both the EGFR itself and downstream RAS/MAPK and PI3K/AKT/TOR signaling cascades.<ref>PMID:22886302</ref> <ref>PMID:23676467</ref> <ref>PMID:23912460</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Arrowsmith, C H]] | ||
| + | [[Category: Bountra, C]] | ||
| + | [[Category: Bufton, J C]] | ||
| + | [[Category: Bullock, A N]] | ||
[[Category: Collins, P]] | [[Category: Collins, P]] | ||
| - | [[Category: | + | [[Category: Delft, F von]] |
| - | [[Category: | + | [[Category: Douangamath, A]] |
| - | + | ||
| - | + | ||
[[Category: Edwards, A]] | [[Category: Edwards, A]] | ||
| - | [[Category: | + | [[Category: Fox, A E]] |
[[Category: Krojer, T]] | [[Category: Krojer, T]] | ||
| - | [[Category: | + | [[Category: Pinkas, D M]] |
| - | [[Category: | + | [[Category: Talon, R]] |
| - | [[Category: | + | [[Category: Zhang, R]] |
| - | [[Category: | + | [[Category: Duf1669 domain]] |
| + | [[Category: Pandda]] | ||
| + | [[Category: Protein binding]] | ||
| + | [[Category: Sgc - diamond i04-1 fragment screening]] | ||
| + | [[Category: Xchemexplorer]] | ||
Revision as of 08:05, 19 December 2018
PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with OX-145
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