5qhp

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m (Protected "5qhp" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 5qhp is ON HOLD
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==PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000554a==
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<StructureSection load='5qhp' size='340' side='right' caption='[[5qhp]], [[Resolution|resolution]] 2.06&Aring;' scene=''>
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Authors: Pinkas, D.M., Bufton, J.C., Fox, A.E., Talon, R., Krojer, T., Douangamath, A., Collins, P., Zhang, R., von Delft, F., Bountra, C., Arrowsmith, C.H., Edwards, A., Bullock, A.N.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5qhp]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QHP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QHP FirstGlance]. <br>
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Description: PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) --Crystal Structure of human FAM83B in complex with FMOPL000554a
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GQM:5-methoxy-2-(1~{H}-pyrazol-3-yl)phenol'>GQM</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qhp OCA], [http://pdbe.org/5qhp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qhp RCSB], [http://www.ebi.ac.uk/pdbsum/5qhp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qhp ProSAT]</span></td></tr>
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[[Category: Zhang, R]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/FA83B_HUMAN FA83B_HUMAN]] Probable proto-oncogene that functions in the epidermal growth factor receptor/EGFR signaling pathway. May activate both the EGFR itself and downstream RAS/MAPK and PI3K/AKT/TOR signaling cascades.<ref>PMID:22886302</ref> <ref>PMID:23676467</ref> <ref>PMID:23912460</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Arrowsmith, C H]]
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[[Category: Bountra, C]]
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[[Category: Bufton, J C]]
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[[Category: Bullock, A N]]
[[Category: Collins, P]]
[[Category: Collins, P]]
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[[Category: Pinkas, D.M]]
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[[Category: Delft, F von]]
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[[Category: Fox, A.E]]
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[[Category: Douangamath, A]]
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[[Category: Arrowsmith, C.H]]
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[[Category: Talon, R]]
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[[Category: Edwards, A]]
[[Category: Edwards, A]]
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[[Category: Douangamath, A]]
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[[Category: Fox, A E]]
[[Category: Krojer, T]]
[[Category: Krojer, T]]
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[[Category: Von Delft, F]]
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[[Category: Pinkas, D M]]
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[[Category: Bountra, C]]
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[[Category: Talon, R]]
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[[Category: Bullock, A.N]]
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[[Category: Zhang, R]]
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[[Category: Bufton, J.C]]
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[[Category: Duf1669 domain]]
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[[Category: Pandda]]
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[[Category: Protein binding]]
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[[Category: Sgc - diamond i04-1 fragment screening]]
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[[Category: Xchemexplorer]]

Revision as of 08:05, 19 December 2018

PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000554a

5qhp, resolution 2.06Å

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