This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5qje
From Proteopedia
(Difference between revisions)
m (Protected "5qje" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of NUDT5 in complex with Z275181224== | |
| - | + | <StructureSection load='5qje' size='340' side='right' caption='[[5qje]], [[Resolution|resolution]] 1.75Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5qje]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QJE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QJE FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K0P:N-[(1-ethyl-1H-pyrazol-4-yl)methyl]pyridine-3-carboxamide'>K0P</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qje FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qje OCA], [http://pdbe.org/5qje PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qje RCSB], [http://www.ebi.ac.uk/pdbsum/5qje PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qje ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NUDT5_HUMAN NUDT5_HUMAN]] Hydrolyzes with similar activities ADP-ribose ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP. Can also hydrolyze other nucleotide sugars with low activity.<ref>PMID:17052728</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Arrowsmith, C H]] | ||
| + | [[Category: Bountra, C]] | ||
| + | [[Category: Burgess-Brown, N]] | ||
[[Category: Collins, P]] | [[Category: Collins, P]] | ||
| - | [[Category: | + | [[Category: Delft, F von]] |
| - | + | ||
| - | + | ||
[[Category: Dubianok, Y]] | [[Category: Dubianok, Y]] | ||
[[Category: Edwards, A]] | [[Category: Edwards, A]] | ||
| + | [[Category: Huber, K]] | ||
| + | [[Category: Krojer, T]] | ||
[[Category: Strain-Damerell, C]] | [[Category: Strain-Damerell, C]] | ||
| - | [[Category: | + | [[Category: Wright, N]] |
| - | [[Category: | + | [[Category: Hydrolase]] |
| - | [[Category: | + | [[Category: Nudt5]] |
| + | [[Category: Pandda]] | ||
| + | [[Category: Sgc - diamond i04-1 fragment screening]] | ||
| + | [[Category: Xchemexplorer]] | ||
Revision as of 08:06, 19 December 2018
PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of NUDT5 in complex with Z275181224
| |||||||||||
